Relationship of bruxism with oral health-related quality of life and facial muscle pain in dentate individuals.

Background: To determine whether there is a correlation of bruxism (sleep, daytime, or both) with oral health-related quality of life and facial pain of muscular origin in dentate individuals. Material and Methods: Seventy-four dentate patients (complete dentition) were included in this study. These individuals had pain in the facial muscles due to temporomandibular disorder (TMD). Smokers; and those with obstructive sleep apnea, TMD of joint origin associated or not with pain, malocclusion, and cancer; and users of illicit drugs, psychiatric medications, and alcohol were excluded. Obstructive sleep apnea, bruxism (of sleep and/or daytime), facial muscle pain, and oral health-related quality of life were assessed by the following questionnaires: Berlin Questionnaire, Pintado et al. questionnaire, VAS (Visual Analog Scale) facial muscle pain questionnaire, and Oral Health Impact Profile - 14. Four groups were created: 1) no bruxism; 2) sleep bruxism; 3) daytime bruxism; and 4) sleep and daytime bruxism. Spearman's correlation test was applied to verify if there was a correlation between the collected data. P values less than 0.05 were considered statistically significant. Results: There was a positive correlation of daytime bruxism with mean pain in the last 3 months (P<0.05) and the worst pain experienced in the last 3 months (P<0.05). Conclusions: Bruxism (sleep, daytime, or both) showed a positive correlation with lower oral health-related quality of life (P<0.05). Key words:Bruxism, facial pain, temporomandibular joint disorders, surveys and questionnaires, health-related quality of life.

Does oral lichen planus aggravate the state of periodontal disease? A systematic review and meta-analysis.

BACKGROUND: The objective of this systematic review and meta-analysis (SRM) was to assess the evidence between the association of oral lichen planus and periodontal disease, evaluating the periodontal clinical parameters and biomarkers levels. METHODS: This systematic review and meta-analysis followed PRISMA and was registered in PROSPERO (CRD42020181513). Searches were accomplished in databases for articles published until June 2021. The meta-analysis was performed with the variables: plaque index (PI), gingival index (GI), probing depth (PD), and clinical attachment loss (CAL). The mean difference was applied with a 95% confidence interval. RESULTS: Six articles were included. Qualitative analysis showed the levels of biomarkers (matrix metalloproteinases, interleukins, and periodontal microbiological profile) are increased in subjects with periodontal disease and oral lichen planus. In the meta-analysis, these subjects also presented increases in all periodontal clinical parameters evaluated: GI-gingivitis 0.22 [0.14, 0.31] p < 0.0001 and periodontitis 0.12 [0.06, 0.19] p = 0.0003; PI-gingivitis 0.22 [0.12, 0.31] p < 0.0001 and periodontitis 0.15 [0.08, 0.23] p < 0.0001; PD-gingivitis 0.27 [0.06; 0.48] p = 0.0107 and periodontitis 0.11 [0.01; 0.21] p = 0.0299; and CA-periodontitis 0.06 [0.01, 0.12] p = 0.0176. CONCLUSIONS: Evidence suggests a significant relationship between the severity of periodontal disease and the presence of oral lichen planus. Although the association is biologically plausible, further studies are needed using populations and well-defined biochemical and clinical outcomes with consideration of potential confounding factors. CLINICAL RELEVANCE: This SRM provides information on the interaction between OLP and periodontal disease and guides clinicians to make evidence-based decisions and suggests recommendations for further high-quality studies.

Does oral lichen planus aggravate the state of periodontal disease? A systematic review and meta-analysis

OBJETIVO: O objetivo desta revisão sistemática e metanálise (SRM) foi avaliar as evidências entre a associação de líquen plano oral (OLP) e doença periodontal, avaliando os parâmetros clínicos periodontais e os níveis de biomarcadores. MATERIAIS E MÉTODOS: Esta revisão sistemática e meta-análise seguiu PRISMA e foi registrada no PROSPERO (CRD42020181513). Foram realizadas buscas em bases de dados de artigos publicados até junho de 2021. A metanálise foi realizada com as variáveis: índice de placa (PI), índice gengival (GI), profundidade de sondagem (PD) e perda de inserção clínica (CAL). A diferença média foi aplicada com intervalo de confiança de 95%. RESULTADOS: 6 artigos foram incluídos. A análise qualitativa mostrou que os níveis de biomarcadores (metaloproteinases de matriz, interleucinas e perfil microbiológico periodontal) estão aumentados em indivíduos com doença periodontal e líquen plano oral. Na metanálise, esses indivíduos também apresentaram aumentos em todos os parâmetros clínicos periodontais avaliados: GI­ gengivite 0,22 [0,14, 0,31] p< 0,0001 e periodontite 0,12 [0,06, 0,19] p=0,0003; PI­ gengivite 0,22 [0,12, 0,31] p< 0,0001 e periodontite 0,15 [0,08, 0,23] p< 0,0001; PD­ gengivite 0,27 [0,06; 0,48] p=0,0107 e periodontite 0,11 [0,01; 0,21] p=0,0299; e CA ­ periodontite 0,06 [0,01, 0,12] p=0,0176. CONCLUSÕES: Evidências sugerem uma relação significativa entre a gravidade da doença periodontal e a presença de líquen plano oral. RELEVÂNCIA CLÍNICA: Este SRM fornece informações sobre a interação entre OLP e a doença periodontal e orienta os médicos a tomar decisões baseadas em evidências e sugere recomendações para estudos adicionais de alta qualidade(AU)

BACKGROUND: The objective of this systematic review and meta-analysis (SRM) was to assess the evidence between the association of oral lichen planus (OLP) and periodontal disease, evaluating the periodontal clinical parameters and biomarkers levels. METHODS: This systematic review and meta-analysis followed PRISMA and was registered in PROSPERO (CRD42020181513). Searches were accomplished in databases for articles published until June 2021. The meta-analysis was performed with the variables: plaque index (PI), gingival index (GI), probing depth (PD), and clinical attachment loss (CAL). The mean difference was applied with a 95% confidence interval. RESULTS: 6 articles were included. Qualitative analysis showed the levels of biomarkers (matrix metalloproteinases, interleukins, and periodontal microbiological profile) are increased in subjects with periodontal disease and oral lichen planus. In the meta-analysis, these subjects also presented increases in all periodontal clinical parameters evaluated: GI­ gingivitis 0.22 [0.14, 0.31] p < 0.0001 and periodontitis 0.12 [0.06, 0.19] p =0.0003; PI­ gingivitis 0.22 [0.12, 0.31] p < 0.0001 and periodontitis 0.15 [0.08, 0.23] p < 0.0001; PD­ gingivitis 0.27 [0.06; 0.48] p=0.0107 and periodontitis 0.11 [0.01; 0.21] p=0.0299; and CA ­ periodontitis 0.06 [0.01, 0.12] p=0.0176. CONCLUSIONS: Evidence suggests a significant relationship between the severity of periodontal disease and the presence of oral lichen planus. CLINICAL RELEVANCE: This SRM provides information on the interaction between OLP and periodontal disease and guides clinicians to make evidence-based decisions and suggests recommendations for further high-quality studies(AU)

Adjuvant therapy with 1% alendronate gel for experimental periodontitis treatment in rats.

PURPOSE: The aim of this study was to evaluate the effects of locally delivered 1% alendronate (ALN) gel used as an adjunct to non-invasive periodontal therapy. METHODS: Ligature-induced periodontitis was performed in 96 rats. The ligature was tied in the cervical area of the mandibular left first molar. The animals were randomly divided into 4 groups: 1) NT, no treatment; 2) SRP, scaling and root planning; 3) SRP/PLA, SRP followed by filling the periodontal pocket with placebo gel (PLA); and 4) SRP/ALN, SRP followed by filling the periodontal pockets with 1% ALN gel. Histomorphometric (percentage of bone in the furcation region [PBF]) and immunohistochemical (receptor activator of nuclear factor-κB ligand, osteoprotegerin, and tartrate-resistant acid phosphatase) analyses were performed. Data were statistically analyzed, with the threshold of statistical significance set at P≤0.05. RESULTS: The SRP, SRP/PLA, and SRP/ALN groups presented a higher PBF than the NT group (P≤0.01) at 7, 15, and 30 days. The SRP/ALN group presented a higher PBF than the SRP/PLA group in all experimental periods, as well as a higher PBF than the SRP group at 15 and 30 days. No differences were observed in the immunohistochemical analyses (P>0.05 for all). CONCLUSIONS: Locally delivered 1% ALN gel used as an adjunct to SRP enhanced bone regeneration in the furcation region in a rat model of experimental periodontitis.

Evaluation of Dental Caries Behavior in Childhood: Health Promotion and Control / Avaliação do Comportamento da Cárie Dentária na Infância: Controle e Promoção de Saúde

Dental caries is still the most common pathology in childhood, caused mainly by lack of adequate prevention. The aim of this project was to evaluate the dental caries profile in children and the importance of multidisciplinary practice in dental caries. Material and methods: 1st stage- meetings were held with the teachers of the child education network and conferences addressed to parents and those responsible for the children. 2nd stage- Assessment and examination of oral health with education process and motivation for dental hygiene. Results: A total of 3390 children were analyzed, of which 859 had carious teeth, that is, 25.34% of the children had caries disease. There is a large presence of caries in the PRE II level, whose highest prevalence of caries is 41.73%, and the lowest recorded in Kindergarten I with 3.11%. This is mainly due to age, directly related to the period in which the basic oral health care program began in day care centers, as older children already had high caries rates when the preventive program was institutionalized to control the occurrences of caries and health promotion. Conclusion: The prevalence of caries in preschool children is still high, but the multidisciplinary approach has shown to be effective and able to reach the levels recommended by ONU 2030 appointment book for dental caries control. (AU)

A cárie dentária é a enfermidade mais comum na infância, causada essencialmente pela falta de prevenção adequada. O objetivo deste estudo foi avaliar o perfil da cárie dentária em crianças e a importância da ação multidisciplinar no controle da mesma. Na primeira fase, foram realizadas reuniões com os professores da rede de educação infantil e conferências dirigidas aos pais e responsáveis das crianças. Na 2ª fase: avaliação e exame de saúde bucal com orientação e motivação para higiene bucal. Foram analisadas 3390 crianças, das quais 859 apresentaram cárie dentária (25,34%). Obervou-se grande presença de cárie no nível PRE II, cuja maior prevalência de cárie é de 41,73%, e a menor registrada no Jardin I com 3,11%. Isso se deve principalmente à idade, relacionada diretamente ao período em que iniciou o Programa Básico de Atenção a Saúde Bucal nas creches, uma vez que as crianças mais velhas já apresentavam altas taxas de cárie quando o programa preventivo foi institucionalizado para controlar ocorrências de cárie e promoção da saúde bucal. Ainda existe alta prevalência de cárie em pré-escolares, entretanto, a abordagem multidisciplinar mostrou-se efetiva e capaz de alcançar os índices preconizados pela Agenda 2030 da ONU para o controle e prevenção da cárie dentária. (AU)

The importance of student monitoring in academic learning: a two-year follow-up

Monitory's exercises must provide conditions that support academic and personal development for students in graduation, once the leveling possibilities in a way that monitors can fill the demand of students in previous seasons. Aim: This study has the goal to investigate the monitory's value in benefit of student's good scholar performance. Methods: In 2015 and 2016 second year Odontology students were monitored for the subject pharmacology. Facing need of accompanied study because high fails percentage. Accompanied theory classes were did weekly, study groups and content review to deal with. After two years of accompany was determined that percentage number of fails. The data were analyzed by variance and Student-Newman-Keuls test (p<0,001). Results: Majority had expressive results, since number of reproves decreased drastically, statically lower than in antecedent years. Conclusion: It was possible to prove that activity has a positive effect in learning for learners making possible access to knowledge and was indispensable for the regiments systematization, seen that advice and monitory students make them develop better skills to learn the disciplines